Anti-Viral CCI – Biotin
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Antibody DetailsProduct DetailsReactive Species viral Host Species Goat Immunogen Sf 21-Derived Recombinant Viral CCI Formulation This biotinylated antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 50 µg of bovine serum albumin per µg of antibody with no calcium, magnesium, or preservatives present. State of Matter Lyophilized Storage and Handling The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months. Country of Origin USA Shipping Next Day Ambient RRIDAB_2828587 Applications and Recommended Usage? Quality Tested by Leinco Western Blotting: To detect Viral CCI this biotin conjugate can be used at a concentration of 0.1 - 0.2 µg/ml. This biotin conjugate should be used in conjunction with compatible second-step reagents such as PN:A106 and a chromogenic substrate such as PN:T343. The detection limit for Viral CCI is 2 ng/lane under either reducing or non-reducing conditions. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Goat Anti-Viral CC Chemokine Inhibitor (CCI) recognizes Viral CCI. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research. Background Viral C-C chemokine inhibitor (vCCI) is a secreted, poxvirus-encoded C-C chemokine inhibitor1 that binds tightly and inhibit the action of many CC chemokines.2 VCCI can act as a potent anti-inflammatory therapeutic.2 Antigen DetailsPubMed References & Citations1. Don, C. et al. (1996) Proc Natl Acad Sci USA 96: 12379 2. LiWang, PJ. et al. (2006) Proc Natl Acad Sci USA 103(38): 13985 Technical Protocols |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
