CA-125 Antigen

CA-125 Antigen

Product No.: 3350

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Product Type
Native Protein
Alternate Names
MUC-16, Ovarian cancer-related tumor marker CA125, CA-125, Ovarian carcinoma antigen CA125

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Antibody Details

Product Details

Host Species
Human
Formulation
20mM Tris-HCl, pH 7.5, 0.1% NaCl, 0.09% sodium azide
State of Matter
lyophilized
Product Preparation
CA-125 purified from human adenocarcinoma; tissue donor tested negative for antibodies to HBsAg, HIV-1, and HIV-2 and negative for HCV and syphilis. Identity of product confirmed by reactivity with specific anti-CA-125 monoclonal antibody.
Storage and Handling
This product is stable for at least one (1) year at -20°C. Store in appropriate aliquots to avoid multiple freeze-thaw cycles.
Country of Origin
USA
Shipping
Next Day 2-8°C
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Background
CA-125 (cancer antigen 125, carcinoma antigen 125, or carbohydrate antigen 125) also known as mucin 16 or MUC16 is encoded by the MUC16 gene in humans. MUC16 is a member of the mucin family of glycoproteins. CA-125 is most consistently elevated in epithelial ovarian cancer, but can be expressed in a number of gynecologic (endometrial, fallopian tube) and non- gynecologic (pancreatic, breast, colon and lung) cancers. It may also be elevated in cases of benign abnormalities such as endometriosis.

Antigen Details

NCBI Gene Bank ID
UniProt.org
Research Area
Cancer Research

References & Citations

Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.