Anti-Human CA-125/MUC16 Antibody (3345)
Anti-Human CA-125/MUC16 Antibody (3345)
Product No.: 3345
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Clone 325 Target CA-125/MUC16 Formats AvailableView All Product Type Monoclonal Alternate Names MUC-16, Ovarian cancer-related tumor marker CA125, CA-125, Ovarian carcinoma antigen CA125 Isotype Mouse IgG1 Applications ELISA , ELISA Det , IHC , WB , IHC-P |
Data
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Antibody DetailsProduct DetailsReactivity Species Human Host Species Mouse Immunogen CA-125 purified from ovarian carcinoma cells. Product Concentration Lot Specific Formulation 10mM Tris buffer, pH 7.5, 0.15M NaCL, 0.05% sodium azide State of Matter Liquid Product Preparation Purified by ion exchange chromatography Storage and Handling These antibodies are stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco These antibodies may be used in ELISA and Western blotting to detect CA-125.
Positive control: OVCAR3 ovarian adenocarcinoma cells.Suggested pairs for sandwich ELISA: Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Mouse Monoclonal Antibody specific to CA-125 Matched Pair Capture: #3346; Detection: #3345 or #3330 Background CA-125 (cancer antigen 125, carcinoma antigen 125, or carbohydrate antigen 125) also known as mucin 16 or MUC16 is encoded by the MUC16 gene in humans. MUC16 is a member of the mucin family of glycoproteins. CA-125 is most consistently elevated in epithelial ovarian cancer, but can be expressed in a number of gynecologic (endometrial, fallopian tube) and non- gynecologic (pancreatic, breast, colon and lung) cancers. It may also be elevated in cases of benign abnormalities such as endometriosis. Antigen DetailsFunction Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. {ECO:0000250}. NCBI Gene Bank ID UniProt.org Research Area Cancer Research References & CitationsChen, Y et al. 1999. PNAS (USA) 96: 4443-4448 Chang, KH et al. 1997. PNAS (USA) 94: 9040-9045. Technical Protocols |
Formats Available
