Anti-Human CA-125/MUC16 Antibody (3330)

Anti-Human CA-125/MUC16 Antibody (3330)

Product No.: 3330

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Clone
X75
Target
CA-125/MUC16
Formats AvailableView All
Product Type
Monoclonal
Alternate Names
MUC-16, Ovarian cancer-related tumor marker CA125, CA-125, Ovarian carcinoma antigen CA125
Isotype
Mouse IgG1
Applications
ELISA
,
ELISA Det
,
WB

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Select Product Size
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Antibody Details

Product Details

Reactivity Species
Human
Host Species
Mouse
Immunogen
CA-125 purified from ovarian carcinoma cells.
Product Concentration
Lot Specific
Formulation
10mM Tris buffer, pH 7.5, 0.15M NaCL, 0.05% sodium azide
State of Matter
Liquid
Product Preparation
Purified by ion exchange chromatography
Storage and Handling
These antibodies are stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
Country of Origin
USA
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco
These antibodies may be used in ELISA and Western blotting to detect CA-125.

Positive control: OVCAR3 ovarian adenocarcinoma cells.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Monoclonal Antibody specific to CA-125
Matched Pair
Capture: #3346; Detection: #3345 or #3330
Background
CA-125 (cancer antigen 125, carcinoma antigen 125, or carbohydrate antigen 125) also known as mucin 16 or MUC16 is encoded by the MUC16 gene in humans. MUC16 is a member of the mucin family of glycoproteins. CA-125 is most consistently elevated in epithelial ovarian cancer, but can be expressed in a number of gynecologic (endometrial, fallopian tube) and non- gynecologic (pancreatic, breast, colon and lung) cancers. It may also be elevated in cases of benign abnormalities such as endometriosis.

Antigen Details

Function
Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. {ECO:0000250}.
NCBI Gene Bank ID
UniProt.org
Research Area
Cancer Research

References & Citations

Indirect Elisa Protocol
ELISA Det
General Western Blot Protocol

Formats Available

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Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.