Recombinant Human CXCL14

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Pricing & Details

Product. No.B381
Alternate Names
Chemokine (C-X-C Motif) Ligand 14, SCYB14, BRAK, NJAC, Bolekine, Kec, MIP-2 Gamma, BMAC, KS1, MGC10687
Expression Host
E. coli
Species
Human
Prod No.
Size
Price
Avail.
Qty
Add to cart
B381-25 μg
25 µg
$349.00
In stock
Max:
Min: 1
Step: 1

Background

Chemokine (C-X-C motif) ligand 14 (CXCL14) is a small cytokine belonging to the CXC chemokine family that is also known as BRAK (for breast and kidney-expressed chemokine).1 CXCL14 is known to be a chemoattractant for monocyte and dendritic cells.2 CXCL14 might play a pivotal role in the pathobiology of pancreatic cancer, probably by regulating cancer invasion.3

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.01EU/µg as determined by the LAL method
Biological Activity
The biological activity of Human BRAK was determined by its ability to induce calcium flux of prostaglandin E2 treated THP-1 cells (Kurth, I. et al., 2001, J. Exp. Med. 194:855). 0.25 μg/mL of rhCXCL14 can significantly induce calcium flux.
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
skckcsrkgp kirysdvkkl emkpkyphce ekmviittks vsryrgqehc lhpklqstkr fikwynawne krrvyee
N-terminal Sequence Analysis
Ser35
State of Matter
Solution
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human CXCL14 is Mr 9.4 kDa.
Formulation
This recombinant protein solution was 0.2 µm filtered and formulated in modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.4 with no calcium, magnesium, or preservatives present.
Storage and Stability
Working aliquots of this recombinant protein solution are stable for up to twelve months at -20°C to -70°C in a manual defrost freezer. Upon thawing, in the presence of a carrier protein, this recombinant protein can be stored at 2° - 8°C for one month without detectable loss of activity. For long-term storage, aliquot and freeze at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles.
Country of Origin
USA
Shipping
Dry Ice
PubMed
NCBI Gene Bank

References & Citations

1. Moser, B. et al. (2004) Cytokine 44: 248
2. Chihara, K. et al. (2007) Biochem Biophys Res Commun. 364: 1037
3. Friess, H. et al. (2008) Cancer Lett. 259: 209
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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