Anti-Human CXCL14

E. coli-Derived Recombinant Human CXCL14

This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.4 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.

The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

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Goat Anti-Human CXCL14 recognizes Human CXCL14. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

Chemokine (C-X-C motif) ligand 14 (CXCL14) is a small cytokine belonging to the CXC chemokine family that is also known as BRAK (for breast and kidney-expressed chemokine).¹ CXCL14 is known to be a chemoattractant for monocyte and dendritic cells.² CXCL14 might play a pivotal role in the pathobiology of pancreatic cancer, probably by regulating cancer invasion.³

1. Moser, B. et al. (2004) Cytokine 44: 248
2. Chihara, K. et al. (2007) Biochem Biophys Res Commun. 364: 1037
3. Friess, H. et al. (2008) Cancer Lett. 259: 209