Anti-Human CXCL14 (Clone 131120)
Anti-Human CXCL14 (Clone 131120)
Product No.: C1460
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Clone 131120 Target CXCL14 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names Chemokine (C-X-C Motif) Ligand 14, SCYB14, BRAK, NJAC, Bolekine, Kec, MIP-2 Gamma, BMAC, KS1 Isotype IgG2a Applications ELISA Cap , WB |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen E. coli-Derived Recombinant Human CXCL14 (Accession # O95715) Endotoxin Level <0.1 EU/µg as determined by the LAL method Formulation This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.4 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. Storage and Handling The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months. Country of Origin USA Shipping Next Day Ambient RRIDAB_2828524 Applications and Recommended Usage? Quality Tested by Leinco Western Blotting: To detect Human CXCL14 this monoclonal antibody can be used at a concentration of 1-2 µg/ml. This monoclonal antibody should be used in conjunction with compatible second-step reagents such as PN:M114 and a chromogenic substrate such as PN:T343. The detection limit for Human CXCL14 is 25 ng/lane under either reducing or non-reducing conditions. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used. Additional Applications Reported In Literature ? ELISA Capture: Suitable for use at concentration of 2-8 µg/mL. Use in combination with: Detection Reagent: Human CXCL14/BRAK Biotinylated Antibody. Standard: Recombinant Human CXCL14/BRAK Protein, CF. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Mouse Anti-Human CXCL14 (Clone 131120) recognizes an epitope on Human CXCL14. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Chemokine (C-X-C motif) ligand 14 (CXCL14) is a small cytokine belonging to the CXC chemokine family that is also known as BRAK (for breast and kidney-expressed chemokine).1 CXCL14 is known to be a chemoattractant for monocyte and dendritic cells.2 CXCL14 might play a pivotal role in the pathobiology of pancreatic cancer, probably by regulating cancer invasion.3 Antigen DetailsPubMed NCBI Gene Bank ID UniProt.org References & Citations1. Moser, B. et al. (2004) Cytokine 44: 248 2. Chihara, K. et al. (2007) Biochem Biophys Res Commun. 364: 1037 3. Friess, H. et al. (2008) Cancer Lett. 259: 209 Technical Protocols  |
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Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
