Recombinant Mouse IL-11

Home/Recombinant Proteins/Recombinant Mouse IL-11

Pricing & Details

Product. No.I-561
Alternate Names
Interleukin-11, AGIF(Adipogenesis Inhibitory Factor)
Expression Host
E. coli
Species
Mouse
Prod No.
Size
Price
Avail.
Qty
Add to cart
I-561-25 µg
25 µg
$939.00
In stock
Max:
Min: 1
Step: 1

Background

Interleukin 11 (IL-11) is a multifunctional cytokine isolated from bone marrow-derived stromal cells. It is a key regulator of multiple events in hemtaopoiesis, most notably the stimulation of megakaryocyte maturation.1 It is also known under the names Adipogenesis inhibitory factor (AGIF)2 and Oprelvekin. IL-11 improves platelet recovery after chemotherapy-induced thrombocytopenia, induces acute phase proteins, modulates antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation and could be use as a therapeutic for osteoporosis. Besides from lymphopoietic/hematopoietic and osteotrophic properties, it has functions in many tissues such as brain, gut and testis.

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
m(gp)pagspr vssdpradld savlltrsll adtrqlaaqm rdkfpadgdh sldslptlam sagtlgslql pgvltrlrvd lmsylrhvqw lrraggpslk tlepelgalq arlerllrrl qllmsrlalp qaapdqpvip lgppasawgs iraahailgg lhltldwavr gllllktrl
N-terminal Sequence Analysis
Met & Pro25
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse IL-11 is Mr 19 kDa.
Formulation
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) and trehalose, pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
PubMed
NCBI Gene Bank

References & Citations

1. Williams, DA. et al. (1990) Proc. Natl. Acad. Sci. USA87: 7512
2. Takiguchi, Y. et al. (1991) FEBS Lett. 283: 199
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Leinco Technologies uses cookies to improve your experience and our website service. By continuing to browse our website, you accept our cookie policy. Ok