Recombinant Mouse MIP-3β

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Pricing & Details

Product. No.M1106
Alternate Names
Macrophage Inflammatory Protein-3β, CCL19, AMAC-1, Ckb7, Ck-Beta 7, DC-CK1, MIP4, PARC, SCYA18, MIP-3B, Exodus-3, EBI1-Ligand Chemokine (ELC)
Expression Host
E. coli
Species
Mouse
Prod No.
Size
Price
Avail.
Qty
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M1106-25 µg
25 µg
$249.00
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Min: 1
Step: 1

Background

Macrophage inflammatory protein-3beta (MIP-3beta) is a non-glycosylated polypeptide and member of the B-chemokine (C-C) family of cytokines. It plays an important role in the inflammatory response of human T cells and tissue macrophages. MIP-3beta is a potential chemoattractant for endometrial natural killer cells.1 It may be important in trafficking of T cells in thymus, and T cell and B cell migration to secondary lymphoid organs.2

Protein Details

Purity
>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<0.01 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Mouse MIP-3β was determined by measured by its ability to chemoattract 5 - 10 day cultured human lymphocytes and BaF/3 cells transfected with hCCR-7. The expected ED50 for these effects are typically 0.03 - 0.1 μg/ml and 3 - 15 ng/ml, respectively.
Expression Host
E. coli
Protein Accession No.
Q548P0
Amino Acid Sequence
ganda edcclsvtqr pipgnivkaf ryllnedgcr vpavvfttlr gyqlcappdq pwvdriirrl kkssaknkgn strrspvlg
N-terminal Sequence Analysis
Gly26
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse MIP-3β is Mr 9.4 kDa.
Formulation
This recombinant protein was lyophilized from a 0.2 μm filtered solution in 30% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank

References & Citations

1. Honjo, H. et al. (2004) Fertil Steril. 1: 876
2. Broxmeyer, HE. et al. (1998) J Immunol. 160: 2418
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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