Anti-Factor V Light Chain Antibody (19701)
Anti-Factor V Light Chain Antibody (19701)
Product No.: 19701
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Clone B38 Target Factor V Light Chain Formats AvailableView All Product Type Monoclonal Alternate Names Activated protein C cofactor, Proaccelerin, labile factor [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain] Isotype Mouse IgG1 Applications ELISA , IHC , Autorad |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen Purified human Factor V. Product Concentration Lot Specific Formulation PBS, pH 7.4 State of Matter Liquid Product Preparation Purified by Protein G affinity chromatography Storage and Handling This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco Western blotting: a band of approx. 74kDa is detected. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Mouse Monoclonal Antibody recognizes the F1F2 polypeptide of human Factor Va light
chain. Background Coagulation cofactor V (Factor V) is a high molecular weight glycoprotein that performs several critical functions in regulating hemostasis. In its thrombin-activated form (FVa) it interacts with Factor Xa and Ca+2 to form the prothrombinase complex. This complex catalyzes the formation of thrombin from prothrombin at rates substantially higher than Factor Xa alone. Function Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin. NCBI Gene Bank ID UniProt.org Research Area Coagulation factors References & CitationsGewirtz AM et al. 1986 Blood 67: 1639-1648. Annamalai AE et al. 1987 Blood 70: 139-156. Technical Protocols  Autorad Certificate of Analysis |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
