Anti-FK-506 Antibody (17301)

Anti-FK-506 Antibody (17301)

Product No.: 17301

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Clone
FK1
Target
FK-506
Formats AvailableView All
Product Type
Monoclonal
Isotype
Mouse IgM
Applications
ELISA,WB

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Antibody Details

Product Details

Reactive Species
Fk-506
Host Species
Mouse
Immunogen
FK-506 conjugated to bovine serum albumin.
Product Concentration
Lot Specific
Formulation
PBS containing 0.1% sodium azide
State of Matter
Liquid
Product Preparation
Purified by immunoaffinity chromatography
Storage and Handling
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Country of Origin
USA
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco
This antibody may be used in ELISA and Western blotting to detect FK-506.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Description

Specificity
Mouse Monoclonal Antibody specific to FK-506
Background
FK-506 is a novel macrolide with similar, but more potent, immunosuppressant activity than cyclosporine. FK-506 is used for primary or rescue immunosuppression in patients after solid organ transplantation. Clinically relevant side effects of FK-506 administration are nephrotoxicity, neurotoxicity, diabetes mellitus, and hypertension. Most of these side effects are related to blood levels of FK-506 rather than dosage. Therefore, therapeutic drug monitoring of FK-506 is a prerequisite for therapy. The whole blood target level range aimed for in clinical practice is 3.0-20.0 ng/ml and depends on the patient's liver function, the nature of organ transplantation, and the time after transplantation.
Research Area
Drugs

References & Citations

Formats Available

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Prod No.
Description
17301
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.