Anti-Gonadotropin Releasing Hormone Mouse Monoclonal Antibody – Library Pack (193101)

Gonadotropin-releasing hormone (GnRH), also known as luteinizing hormone-releasing hormone (LHRH), is a 10 amino acid neurohormone produced in the hypothalamus. GnRH stimulates the synthesis and secretion of the two gonadotropins—luteinizing hormone (LH) and follicle stimulating hormone (FSH)—by the anterior pituitary gland. Characteristic of all releasing hormones, and most striking in the case of GnRH, is the phenomenon of pulsatile secretion. Under normal circumstances, GnRH is released in pulses at intervals of about 90 to 120 minutes. Abnormalities in the pulsatile secretion of GnRH result in subnormal fertility and abnormal or absent menstruation. Constant administration of GnRH suppresses gonadotropin secretion, which has therapeutic benefits in certain patients, such as children with precocious puberty and men with prostate cancer.

Purified human gonadotropin releasing hormone

These antibodies recognize human GnRH.

Antibodies are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.

Anti-Gonadotropin Releasing Hormone Mouse Monoclonal Antibody Library Pack - Includes 100 ug of each of the following antibodies:

19301 - Anti-Gonadotropin Releasing Hormone Mouse Monoclonal Antibody - Clone LHRH13-327.8 - Isotype IgG1

19302 - Anti-Gonadotropin Releasing Hormone Mouse Monoclonal Antibody - Clone LHRH13-372.14 - Isotype IgG1

19303 - Anti-Gonadotropin Releasing Hormone Mouse Monoclonal Antibody - Clone LHRH13-387.5 - Isotype IgG1

19304 - Anti-Gonadotropin Releasing Hormone Mouse Monoclonal Antibody - Clone LHRH13-426.12 - Isotype IgG1

Upon initial thawing, appropriately aliquot and store at -80°C. For long-term storage, keep at -80°C. Avoid repeated freeze-thaw cycles.