This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Applications and Recommended Usage ?
(Quality Tested by Leinco)
Western Blotting: APRIL can be used for detection of APRIL by Western blot at 5 - 10 μg/mL. A 27 kDa band can be detected.
Rabbit Anti-Human APRIL recognizes an epitope in the extracellular domain of Human APRIL. This polyclonal antibody was purified using affinity chromatography.
A proliferation-inducing ligand (APRIL) is a TNF-like cytokine that stimulates tumor cell growth.1 It is of low abundance in normal tissues.2 APRIL acts as a proliferative factor in megakaryocytopoiesis, a developmental hematopoietic process responsible for progenitor cell differentiation to megakaryoblasts and megakaryocytes, leading to platelet formation.3 APRIL may be implicated in the regulation of tumor cell growth.2
NCBI Gene Bank ID
References & Citations
1. Sarah G. Hymowitz et al. (2004) J Mol Biol. 343: 283 2. (1998) Jürg Tschopp 3. Ruggero De Maria et al. (2004) Blood 104: 3169
Products are for research use only. Not for use in diagnostic or therapeutic procedures.