Anti-Human CD119 (IFN-γ Rα Chain) [Clone GIR-208] — Alexa Fluor® 488
Anti-Human CD119 (IFN-γ Rα Chain) [Clone GIR-208] — Alexa Fluor® 488
Product No.: I-969AF
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Clone GIR-208 Target IFNγ Rα Formats AvailableView All Product Type Hybridoma Monoclonal Antibody Alternate Names Interferon Gamma R Alpha Chain, CDw119, IFN-γR Isotype Mouse IgG1 κ Applications FC |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen Purified Recombinant Human IFNGR1 (>98%) Product Concentration 0.2 mg/ml Formulation This Alexa Fluor® 488 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Alexa Fluor® is a trademark of Life Technologies Corporation. State of Matter Liquid Storage and Handling This Alexa Fluor® 488 conjugate is stable when stored at 2-8°C. Do not freeze. Regulatory Status Research Use Only Country of Origin USA Shipping 2-8°C Wet Ice Excitation Laser Blue Laser (488 nm) Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm. Applications and Recommended Usage? Quality Tested by Leinco FC The suggested concentration for clone GIR-208 conjugated antibody for staining cells in flow cytometry is ≤ .25 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Clone GIR-208 recognizes an epitope on human IFNγ Rα. Background IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription. Antigen Distribution The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes. NCBI Gene Bank ID UniProt.org Research Area Immunology References & CitationsTechnical Protocols Certificate of Analysis |
Formats Available
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Prod No. | Description |
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I-977 | |
I-442 | |
I-969 | |
I-970 | |
I-971 | |
I-975 | |
I-441 | |
I-443 | |
I-973AF | |
I-969AF | |
G737 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
