Anti-Human CD119 (IFN-γ Rα Chain) – DyLight® 594

Anti-Human CD119 (IFN-γ Rα Chain) – DyLight® 594

Product No.: I-971

[product_table name="All Top" skus="I-971"]

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Clone
GIR-208
Target
IFNγ Rα
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
Interferon Gamma R Alpha Chain, CD119
Isotype
IgG1
Applications
FC

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Immunogen
Purified Recombinant Human IFNGR1 (>98%)
Product Concentration
0.2 mg/ml
Formulation
This DyLight® 594 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This DyLight® 594 conjugate is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day 2-8°C
Excitation Laser
Red Laser (590 nm)
Applications and Recommended Usage?
Quality Tested by Leinco
FC The suggested concentration for clone GIR-208 conjugated antibody for staining cells in flow cytometry is ≤ .25 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Clone GIR-208 recognizes an epitope on human IFNγ Rα.
Background
IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
Antigen Distribution
The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.

Antigen Details

NCBI Gene Bank ID
Research Area
Immunology
Flow Cytometry

Certificate of Analysis

Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.