Antibody DetailsProduct DetailsReactivity Species Human Host Species Mouse Product Concentration 0.5 mg/ml Formulation This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Shipping Next Day Ambient RRIDAB_2830691 Applications and Recommended Usage? Quality Tested by Leinco FC The suggested concentration for clone GIR-208 purified antibody for staining cells in flow cytometry is ≤ 0.5 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. Other Applications Reported In Literature ? FA The Purified antibody is recommended for functional assays. Clone GIR-208 can be used as an isotype with Clone MAR1-5A3 (Anti-Mouse IFNAR1) Additional Reported Applications For Relevant Conjugates ? WB IP IHC B Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Clone GIR-208 recognizes an epitope on human IFNγ Rα. Antigen Distribution The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes. Background IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription. Antigen DetailsProtein PubMed Research Area Immunology Technical Protocols |
Formats Available
Prod No. | Description |
|---|---|
I-977 |
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I-442 |
|
I-969 |
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I-970 |
|
I-971 |
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I-973 |
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I-975 |
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I-441 |
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I-443 |
|
G737 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.