Anti-Human Eotaxin (CT)

This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.

This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Rabbit Anti-Human Eotaxin recognizes an epitope near the C-terminus of Human Eotaxin. This polyclonal antibody was purified using affinity chromatography.

The CC-chemokine eotaxin is a potent eosinophil chemoattractant that stimulates recruitment of eosinophils from the blood to sites of allergic inflammation.¹
Eotaxin and related molecules are potentially important endogenous signaling substances in allergic reactions.² Eotaxin plays an important role not only by attracting eosinophils to the site of inflammation but also by damaging tissue by its capacity to induce the release of reactive oxygen species.³

1. Rankin SM. et al. (1998) Blood. 91:2240 2. Williams TJ. et al. (1993) Biochem Biophys Res Commun. 197:1167 3. Kapp A. et al. (1996) Eur J Immunol. 26:1919