Anti-Human IL-1RAcP (CT-2)

Anti-Human IL-1RAcP (CT-2)

Product No.: I-306

[product_table name="All Top" skus="I-306"]

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Target
Interleukin-1 Receptor Accessory Protein
Product Type
Polyclonal Antibody
Alternate Names
IL1RAP
Applications
WB

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Data

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
PN:I-319
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human IL-1 Receptor Accessory Protein (IL-1RAcP) recognizes an epitope near the C-terminus of Human IL-1RAcP. This polyclonal antibody was purified using affinity chromatography.
Background
IL-1R accessory protein (IL-1RAcP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction. IL-1RAcP is an indispensible molecule in the IL-1 receptor signal transduction complex, necessary to link events on the plasma membrane level to downstream signaling pathways, allowing IL-1-dependent activation of transcription factors and gene expression.1 IL-1R AcP represents a novel target for blocking IL-1 function in human disease.2

Antigen Details

References & Citations

1. Martin, MU. et al. (1997) J Biol Chem. 272: 7727
2. Labow, MA. et al. (1998) J Immunol. 161: 5614
General Western Blot Protocol
Products are for research use only. Not for use in diagnostic or therapeutic procedures.