Anti-Human p34cdc2 Serine/Threonine Kinase – DyLight® 650
Anti-Human p34cdc2 Serine/Threonine Kinase – DyLight® 650
Product No.: P316
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Clone 17 Target p34cdc2 Serine/Threonine Kinase Formats AvailableView All Product Type Monoclonal Antibody Isotype IgG2a Applications FC |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen Purified Recombinant Human p34cdc2 Serine/Threonine Kinase (>98%) Product Concentration 0.2 mg/ml Formulation This DyLight® 650 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This DyLight® 650 conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day 2-8°C Excitation Laser Red Laser (652 nm) RRIDAB_2831603 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Mouse Anti-Human p34cdc2 Serine/Threonine Kinase (Clone 17) recognizes an epitope on Human p34cdc2 Serine/Threonine Kinase. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background p34cdc2 is thought to be activated by cyclin through dephosphorylation at tyrosine residues. Activated p34cdc2 kinase is involved in a number of mitotic events such as nuclear envelope breakdown and chromosome condensation through phosphorylation of serine/threonine residues of substrates such as nuclear lamins, histones, pp60c-src, nucleolin and RNA polymerase II. It is then inactivated by a tyrosine kinase. Anti-p34cdc2 can be used in western blotting, immunoprecipitation and immunohistochemistry.
The antibody precipitates an active kinase. NCBI Gene Bank ID UniProt.org Research Area Apoptosis . Cell Biology References & Citations1. Moreno, S. et al. (1990) Cell 61:549 2. Ward, GE. et al. (1990) Cell 61:561 3. Langan, TA. et al. (1989) Mol. Cell. Biol. 9:3860 Technical ProtocolsCertificate of Analysis |
Formats Available
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Prod No. | Description |
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P312 | |
P313 | |
P314 | |
P316 | |
P318 | |
P115 | |
P117 | |
P116 | |
P118 |
