Anti-Human p34cdc2 Serine/Threonine Kinase Purified

Home/Primary Monoclonal Antibodies/Apoptosis & Cell Biology/Anti-Human p34cdc2 Serine/Threonine Kinase Purified

Pricing & Details

Product No.P115
Clone
17
Protein
p34cdc2 Serine/Threonine Kinase
Formats AvailableView All
Product Type
Monoclonal Antibody
Isotype
Mouse
IgG2a
Applications
IHC FFPE
,
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
P115-0.25 mg
0.25 mg
$170.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Mouse
Product Concentration
0.5 mg/ml
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This purified antibody is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day 2-8°C
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Anti-Human p34cdc2 Serine/Threonine Kinase (p34cdc2 Serine/Threonine Kinase) (Clone 17) recognizes an epitope on Human p34cdc2 Serine/Threonine Kinase near the C-terminus in human, mouse, or xenopus cells. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background
p34cdc2 is thought to be activated by cyclin through dephosphorylation at tyrosine residues. Activated p34cdc2 kinase is involved in a number of mitotic events such as nuclear envelope breakdown and chromosome condensation through phosphorylation of serine/threonine residues of substrates such as nuclear lamins, histones, pp60c-src, nucleolin and RNA polymerase II. It is then inactivated by a tyrosine kinase. Anti-p34cdc2 can be used in western blotting, immunoprecipitation and immunohistochemistry. The antibody precipitates an active kinase.

Antigen Details

Research Area
Apoptosis
.
Cell Biology
.
Immunology

References & Citations

1. Moreno, S. et al. (1990) Cell 61:549
2. Ward, GE. et al. (1990) Cell 61:561
3. Langan, TA. et al. (1989) Mol. Cell. Biol. 9:3860
IHC
General Western Blot Protocol

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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