Anti-Human Vitronectin Antibody (42025)
Anti-Human Vitronectin Antibody (42025)
Product No.: 42025
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Clone VN58-1 Target Vitronectin Formats AvailableView All Product Type Monoclonal Alternate Names VN, S-protein, Serum-spreading factor, V75 [Cleaved into: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin-B] Isotype IgG1 Applications ELISA , IHC , WB |
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Antibody DetailsProduct DetailsReactivity Species Human Host Species Mouse Immunogen Human Vitronectin Formulation 10 mM PBS, 1% BSA, pH 7.4, lyophilized State of Matter Lyophilized Product Preparation Purified by immunoaffinity chromatography Storage and Handling The stock solution (2. 0mg/ml) can be stored in aliquots at - 20°C for 1 year or can be stored at 4°C for 6 months after adding 0.1% sodium azide. Dilutions of stock solution should not be stored. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco ELISA: 1:3,000 dilution with solid phase antigen
Western Blot: 5-10 ug/ml under reduced and non-reduced conditions. Immunohistochemistry: 5-10 ug/ml on paraffin embedded and frozen tissue sections. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Mouse monoclonal antibody that specifically reacts with an
epitope in the region of amino acids 1-
130 of human vitronectin. It does not
react with bovine vitronectin, and this
antibody does not interfere with
vitronectin-mediated adhesion. Antigen DetailsFunction Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.; Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity. NCBI Gene Bank ID UniProt.org Research Area Cell Adhesion References & CitationsAng XM et al. Macromolecular Crowding Amplifies Adipogenesis of Human Bone Marrow- Derived Mesenchymal Stem Cellsby Enhancing the Pro-Adipogenic Microenvironment. Tissue Engineering Part A Volume 20: 966, 2014. Western blottingGorur A. et al. COPII-coated membranes function as transport carriers of intracellular procollagen I. J Cell Biol April 20, 2017, PMID 28428367. Immunofluorescence Technical Protocols |
Formats Available
