Anti-Measles Phosphoprotein Antibody (90019)
Anti-Measles Phosphoprotein Antibody (90019)
Product No.: 90019
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Clone 9H4 Target Measles Phosphoprotein Formats AvailableView All Product Type Monoclonal Alternate Names Protein P Isotype IgG1 Applications ELISA , ICC , WB |
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Antibody DetailsProduct DetailsReactivity Species Measles Virus Host Species Mouse Immunogen Recombinant Measles virus phosphoprotein. Formulation Lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose, 1mg/ml. State of Matter Lyophilized Product Preparation Purified by Protein A affinity chromatography Storage and Handling This product is stable for at least one (1) year at -20°C to -70°C. Reconstituted product should be stored in appropriate aliquots to avoid repeated freeze-thaw cycles. Country of Origin USA Shipping Next Day 2-8°C Applications and Recommended Usage? Quality Tested by Leinco ELISA: use at 0.1-1.0ug/ml
Immunoblotting: User should use at 1-5ug/ml. A band of ~70kDa is detected Immunocytochemistry: use at 2- 10ug/ml on virus-infected cells. These are recommended concentrations. End user should determine optimal concentrations for their applications. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Mouse Monoclonal Antibody specific to Measles Phosphoprotein Background Measles virus (MeV) is an enveloped RNA virus in the Morbillivirus genus of the Paramyxoviridae family. Its non- segmented, negative-sense, single- stranded RNA genome is encapsidated by the viral nucleoprotein (N) within a helical nucleocapsid. Transcription and replication are carried out on this N:RNA complex by the viral polymerase complex which consists of two components, the large protein (L) and the phosphoprotein (P). MeV N consists of two regions: a structured N-terminal moiety, NCORE (aa 1–400), which contains all the regions necessary for self-assembly and RNA-binding, and a C-terminal domain, NTAIL(aa 401–525) that is intrinsically unstructured and is exposed at the surface of the viral nucleocapsid. Antigen DetailsFunction Essential component of the RNA polymerase and the nascent chain assembly complex. Also required during RNA synthesis. NCBI Gene Bank ID UniProt.org Research Area Infectious Disease References & CitationsTechnical Protocols ICC  |
Formats Available
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
