Anti-Mouse CD152 (CTLA-4) [Clone 9H10] — CF®700
Anti-Mouse CD152 (CTLA-4) [Clone 9H10] — CF®700
Product No.: C1754CF
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Syrian Hamster Immunogen Purified Recombinant Mouse CTLA-4 (>98%) Product Concentration 0.2 mg/ml Formulation This CF®700 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. State of Matter Liquid Storage and Handling This CF®700 conjugate is stable when stored at 2-8°C, protected from light. Do not freeze. Regulatory Status Research Use Only Country of Origin USA Shipping 2-8°C Wet Ice Excitation Laser 633, 635, 680, or 685 nm Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Clone 9H10 recognizes an epitope on mouse CTLA-4. Background CTLA-4 is a 33 kD member of the Ig superfamily similar to CD28 in amino acid sequence, structure, and genomic organization. CTLA-4 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is involved in the development of protective immunity and thymocyte regulation, in addition to the induction and maintenance of immunological tolerance. CTLA-4 has therapeutic potential both as an agonist to reduce immune activity, and an antagonist to increase immune activity. Antigen Distribution CTLA-4 is expressed on activated T and B lymphocytes. Ligand/Receptor CD80 (B7-1), CD86 (B7-2) PubMed NCBI Gene Bank ID UniProt.org Research Area Immunology References & CitationsTechnical Protocols Certificate of Analysis |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
