Anti-Mouse CD152 (CTLA-4) – DyLight® 755

Pricing & Details

Product No.C1754
Clone
9H10
Protein
CTLA-4
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
CD152, CTLA4
Isotype
Syrian Hamster
IgG
Applications
FC
Prod No.
Size
Price
Avail.
Qty
Add to cart
C1754-50 µg
50 µg
$85.00
In stock
Max:
Min: 1
Step: 1
C1754-100 µg
100 µg
$150.00
In stock
Max:
Min: 1
Step: 1
C1754-200 µg
200 µg
$250.00
In stock
Max:
Min: 1
Step: 1

Antibody Details

Product Details

Reactivity Species
Mouse
Host Species
Syrian Hamster
Immunogen
Purified Recombinant Mouse CTLA-4 (>98%)
Product Concentration
0.5 mg/ml
Formulation
This DyLight® 755 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This DyLight® 755 conjugate is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Clone 9H10 recognizes an epitope on mouse CTLA-4.
Antigen Distribution
CTLA-4 is expressed on activated T and B lymphocytes.
Background
CTLA-4 is a 33 kD member of the Ig superfamily similar to CD28 in amino acid sequence, structure, and genomic organization. CTLA-4 is a protein receptor that functions as an immune checkpoint and downregulates immune responses. It is involved in the development of protective immunity and thymocyte regulation, in addition to the induction and maintenance of immunological tolerance. CTLA-4 has therapeutic potential both as an agonist to reduce immune activity, and an antagonist to increase immune activity.

Antigen Details

Protein
Ligand/Receptor
CD80 (B7-1), CD86 (B7-2)
PubMed
NCBI Gene Bank ID
Research Area
Immunology
Flow Cytometry

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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