Anti-Mouse CD70 – APC

Pricing & Details

Product No.C2405
Clone
FR70
Protein
CD70
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
TNFSF7, KI-24 antigen, CD27 Ligand, CD27L
Isotype
Rat
IgG2b
Applications
FA
,
FC
Prod No.
Size
Price
Avail.
Qty
Add to cart
C2405-25 µg
25 µg
$247.00
Pre-order
Max:
Min: 1
Step: 1
C2405-100 µg
100 µg
$500.00
Pre-order
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Mouse
Host Species
Rat
Immunogen
BALB/c mouse B lymphoma A20.J2
Product Concentration
0.2 mg/ml
Formulation
This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This APC conjugate is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day 2-8°C
Excitation Laser
Red Laser (650 nm)
Applications and Recommended Usage?
Quality Tested by Leinco
FC The suggested concentration for this FR70 antibody for staining cells in flow cytometry is ≤ .25 μg per 106 cells in a volume of 100 μl. Titration of the reagent is recommended for optimal performance for each application.
Additional Reported Applications For Relevant Conjugates ?
IP
B
IHC (Frozen)
For specific conjugates of this clone, review literature for suggested application details.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Clone FR70 recognizes an epitope on mouse CD70.
Antigen Distribution
CD70 is expressed by highly activated lymphocytes as found in T-cell and B-cell lymphomas.
Background
CD70 is a 30-33 kD type II transmembrane glycoprotein and a member of the TNF superfamily. CD70 is the ligand for CD27; the binding of which delivers costimulatory signals to T cells and NK cells. CD70 is expressed on highly activated lymphocytes characteristic of T- and B-cell lymphomas. Because normal lymphocytes have low CD70 expression, it has been suggested that anti-CD70 antibodies may be a possible treatment for CD70 positive lymphomas. CD70-specific antibodies are currently under investigation for the treatment of hematological malignancies and renal cell carcinoma.

Antigen Details

Protein
Ligand/Receptor
CD27
PubMed
NCBI Gene Bank ID
Research Area
Costimulatory Molecules
.
Immunology
Flow Cytometry

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Leinco Technologies uses cookies to improve your experience and our website service. By continuing to browse our website, you accept our cookie policy. Ok