Anti-Mouse CD90 (Thy-1) (Clone HK2.1) – Purified in vivo GOLD™ Functional Grade

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Based on the search results, the HK2.1 clone referenced appears to be an Anti-Mouse CD90 (Thy-1) Clone HK2.1 purified antibody product.

Storage Temperature Requirements

For the sterile packaged HK2.1 clone, the correct storage temperature is 2-8°C for short-term storage of up to one month. This temperature range is standard for functional grade preclinical antibodies when stored sterile as received.

Extended Storage Considerations

While the search results mention that longer term storage options exist for this type of product, the specific temperature requirements for extended storage periods are not detailed in the available information. For optimal preservation of the sterile packaged clone's functionality and stability, maintaining the 2-8°C range is the established protocol for immediate use scenarios.

The 2-8°C storage temperature ensures the sterile packaging maintains product integrity while preserving the biological activity of the HK2.1 clone antibody until it's ready for experimental use.

Commonly used antibodies or proteins in the literature with HK2.1 (interpreted here as the canonical hexokinase 2 (HK2) antibody) often include markers involved in metabolism, stemness, cell signaling, and loading controls in Western blot and immunofluorescence studies.

Frequently co-used primary antibodies and proteins include:

• Metabolic and glycolytic proteins:

  • HK1 (hexokinase 1)
  • PDK1 (pyruvate dehydrogenase kinase 1)
  • PGK1 (phosphoglycerate kinase 1)
  • PFKP (phosphofructokinase, platelet type)
  • COX IV (cyclooxygenase IV, mitochondrial marker)
  • PKM2 (pyruvate kinase M2)
  • GLUT1 (glucose transporter 1)
  • LDHA (lactate dehydrogenase A)

• Stemness and pluripotency markers:

  • Lin28
  • Nanog
  • Oct4
  • CD133

• Ubiquitin pathway and tags:

  • Ubiquitin
  • USP11 (ubiquitin specific peptidase 11)
  • HA (hemagglutinin tag)
  • Flag (epitope tag)
  • GST (glutathione S-transferase tag)

• Loading controls and cell structure:

  • Tubulin
  • GAPDH (glyceraldehyde 3-phosphate dehydrogenase)

The pairing of HK2 with these antibodies often aims to:

• Contrast HK2 with HK1 during metabolic studies or cancer research, especially in engineered cell lines that differentially express these isoforms.
• Assess broader changes in metabolic state or stemness alongside HK2 function.
• Control for protein input or normalization in biochemical assays.

If your context is a specific disease or experimental technique, marker selection may further include disease-relevant proteins or pathway components.

The query seems to refer to "clone HK2.1," but there isn't specific information about it in the provided search results. However, I can provide some insights based on related topics:

1. Hexokinase II (HK2):

   • Cancer Research: Hexokinase II (HK2) is a key enzyme involved in the first step of glycolysis, which is often altered in cancer cells. Studies have shown that HK2 expression differs significantly between tumors and normal tissues, with frequent alterations in certain cancers like UCEC and SKCM.

2. Kallikrein 2 (hK2):

   • Prostate Cancer: Human Kallikrein 2 (hK2) is overexpressed in prostate cancer and has been identified as a potential therapeutic target. Research indicates robust expression of hK2 across different stages of prostate cancer, with potential for hK2-targeting agents in treatment.

If "clone HK2.1" refers to specific research in these areas, further details would be needed to provide more precise findings. However, the literature does highlight the importance of HK2 and hK2 in cancer biology, particularly in the context of metabolic alterations and potential therapeutic targets.