Anti-Mouse GDF-5 (Clone 90509)

Anti-Mouse GDF-5 (Clone 90509)

Product No.: G679

[product_table name="All Top" skus="G679"]

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Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
CDMP1, LAP4, SYNS2, Growth Differentiation Factor 5

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Antibody Details

Product Details

Reactive Species
Host Species
E. coli-Derived Monomeric Recombinant Mouse GDF-5 Peptide
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Storage and Handling
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Country of Origin
Next Day Ambient
Applications and Recommended Usage?
Quality Tested by Leinco
Western Blotting: To detect Mouse GDF-5 this monoclonal antibody can be used at a concentration of 1-2 µg/ml. This monoclonal antibody should be used in conjunction with compatible second-step reagents such as PN:R377 and a chromogenic substrate such as PN:T343. The detection limit forrmGDF-5 and rmGDF-6 is approximately 5 ng/lane and 25 ng/lane under non-reducing and reducing conditions, respectively. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.


Rat Anti-Mouse Growth Differentiation Factor 5 (GDF-5) (Clone 90509) recognizes an epitope on Mouse GDF-5. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Growth differentiation factor 5 (cartilage-derived morphogenetic protein-1), also known as GDF5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. GDF5 is expressed in the developing central nervous system.1 It increases the survival of neurones that respond to a neurotransmitter called dopamine, and is a potential therapeutic molecule associated with Parkinson's disease.2

Antigen Details

NCBI Gene Bank ID

References & Citations

1. Sullivan, A. et al. (2004) J Neurocytol 33: 479
2. O'Keeffe, G. et al. (2005) J Anat 207: 219
General Western Blot Protocol

Formats Available

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Prod No.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.