Anti-SARS-CoV-2 Envelope (NT)

Anti-SARS-CoV-2 Envelope (NT)

Product No.: S537

[product_table name="All Top" skus="S537"]

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Target
SARS-CoV-2
Product Type
Polyclonal Antibody
Alternate Names
SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope Antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Envelope protein, E protein
Isotype
IgG
Applications
ELISA

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Data

Direct ELISA
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Antibody Details

Product Details

Reactive Species
Virus
Host Species
Rabbit
Immunogen
Anti-SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope antibody was raised against a peptide corresponding to 10 amino acids near the amino terminus of SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope protein. The immunogen is located within the first 50 amino acids of SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope.
Product Concentration
1.0 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Applications and Recommended Usage?
Quality Tested by Leinco
ELISA
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-SARS-CoV-2 E recognizes SARS-CoV-2 E. This polyclonal antibody was purified using affinity chromatography.
Background
A coronavirus, SARS-CoV-2, was first identified in 2019 (COVID-19). Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS-CoV-2 can be mediated by the binding of the viral spike protein, a glycosylated protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2.

Antigen Details

NCBI Gene Bank ID
Research Area
COVID-19
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Seasonal and Respiratory Infections
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Viral

References & Citations

1. Gorbalenya. bioRxiv: (2020). 2. Hui et al. Int J Infect Dis. (2020);91:264-266. 3. Pervushin et al. PLoS Pathog. (2009); 5(7): e1000511.
Indirect Elisa Protocol
Products are for research use only. Not for use in diagnostic or therapeutic procedures.