Recombinant Human CD6

CD6 (Cluster of Differentiation 6) is a cell surface glycoprotein that is involved in T cell activation¹ and a member of the scavenger receptor cysteine rich protein superfamily (SRCRSF).² CD6 can deliver coactivating signals to mature T lymphocytes and regulate its antigen specific and autoreactive responses.³

Fc Fusion Protein

hps pappdqlnts saeselwepg erlpvrltng ssscsgtvev rleaswepac galwdsraae avcralgcgg aeaasqlapp tpelppppaa gntsvaanat lagapallcs gaewrlcevv ehacrsdgrr arvtcaenra lrlvdgggac agrvemlehg ewgsvcddtw dledahvvcr qlgcgwavqa lpglhftpgr gpihrdqvnc sgaeaylwdc pglpgqhycg hkedagvvcs ehqswrltgg adrcegqvev hfrgvwntvc dsewypseak vlcqslgcgt averpkglph slsgrmyysc ngeeltlsnc swrfnnsnlc sqslaarvlc sasrslhnls tpevpasvqt vtiessvtvk ienkesredi egrmdpkscd kthtcppcpa pellggpsvf lfppkpkdtl misrtpevtc vvvdvshedp evkfnwyvdg vevhnaktkp reeqynstyr vvsvltvlhq dwlngkeykc kvsnkalpap iektiskakg qprepqvytl ppsrdeltkn qvsltclvkg fypsdiavew esngqpenny kttppvldsd gsfflysklt vdksrwqqgn vfscsvmhea lhnhytqksl slspgkhhhh hh

His18

Lyophilized

The predicted molecular weight of Recombinant Human CD6 is Mr 68.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 110 kDa.

68.2

This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.

This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Next Day Ambient

1. Parnes, JR. et al. (1995) Eur J Immunol. 25: 2765
2. Bajorath, J. et al. (1997) Biochemistry 36: 2637
3. Fox, DA. et al. (1996) Immunology 88: 537