Recombinant Human Resistin

Recombinant Human Resistin

Product No.: R1274

[product_table name="All Top" skus="R1274"]

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Alternate Names
ADSF, Adipose Tissue- Specific Secretory Factor, FIZZ3, Found in Inflammatory Zone, XCP1
Product Type
Recombinant Protein
Expression Host
E. coli Cells
Species
Human

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Product Size
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Background

Resistin is a cysteine-rich protein secreted by adipose tissue of mice and rats. In other mammals, at least primates, pigs and dogs, resistin is secreted by immune and epithelial cells. Resistin is also known as CEBPE regulated myeloid-specific secreted cysteine-rich protein precursor 1 (XCP1), found in inflammatory zone 3 (FIZZ3), or "adipocyte-specific secretory factor" (ADSF). The length of the resistin pre-peptide in human is 108 aminoacids (in the mouse and rat it's 114 aa). Among the proteins synthesized and released from adipose tissue (adiponectin, angiotensin, estradiol, IL-6 [disambiguation needed], leptin, PAI-1, TNF-α), resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM).

Protein Details

Purity
>95% by SDS Page and HPLC
Endotoxin Level
<0.1 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Human Resistin was determined its ability to stimulate lipolysis in human adipocytes.
Protein Accession No.
Amino Acid Sequence
MSSKTLCSME EAINERIQEV AGSLIFRAIS SIGLECQSVT SRGDLATCPR GFAVTGCTCG SACGSWDVRA ETTCHCQCAG MDWTGARCCR VQP
State of Matter
Lyophilized
Predicted Molecular Mass
The predicted molecular weight of Recombinant Human Resistin is Mr 19.5 kDa.
Predicted Molecular Mass
19.5
Formulation
This recombinant protein was lyophilized from a 0.2 μm filtered solution of 0.1% trifluoroacetic acid (TFA).
Storage and Stability
The lyophilized protein should be stored desiccated at -20°C. The reconstituted protein can be stored for at least one week at 4°C. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
NCBI Gene Bank
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.