Anti-Mouse Resistin

Purified Recombinant Mouse Resistin (>98%)

This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.

The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

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Immunohistochemistry: Suitable for use at concentration of 5-15 µg/mL.

Goat Anti-Mouse Resistin recognizes Mouse Resistin. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

Resistin (RETN) is a peptide hormone secreted by adipocytes ¹ with potential roles in insulin resistance and adipocyte differentiation.² Resistin functions as a regulator of glucose homeostasis and a physiologic antagonist to hepatic insulin action.³ Resistin may be an important candidate mediator of obesity-induced insulin resistance.⁴ It may also represent a novel link between metabolic signals, inflammation, and atherosclerosis.⁵

1. Rader, DJ. et al. (2005) Circulation 111: 932
2. Chen, R. et al. (2004) Eur J Endocrinol. 150: 885
3. Wolf, G. et al. (2004) Nutr Rev. 62: 389
4. Lazar, MA. et al. (2002) J Biol Chem. 277: 19754
5. Lazar, MA. et al. (2001) J Biol Chem. 276: 25970