Recombinant Human TRAIL R3
Recombinant Human TRAIL R3
Product No.: T402
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Alternate Names TNF-Related Apoptosis-Inducing Ligand Receptor 3, TRID, TNFRSF10C, CD263, DCR1, LIT, MGC149501, MGC149502 Product Type Recombinant Protein Expression Host NS0 Cells Species Human Applications ELISA Cap |
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BackgroundTNF-related apoptosis-inducing ligand receptor 3 (TRAIL R3) is an antagonist decoy receptor1 that can inhibit TRAIL-induced apoptosis.2 TRAIL R3 is a plasma membrane-bound protein capable of high affinity interaction with the TRAIL ligand.3 Protein DetailsPurity >95% by SDS-PAGE and analyzed by silver stain. Endotoxin Level <0.01EU/µg as determined by the LAL method Fusion Protein Tag Fc Fusion Protein Protein Accession No. Amino Acid Sequence attar qeevpqqtva pqqqrhsfkg eecpagshrs ehtgacnpct egvdytnasn nepscfpctv cksdqkhkss ctmtrdtvcq ckegtfrnen spemcrkcsr cpsgevqvsn ctswddiqcv eefganatve tpaaeetmnt spgtpapaae etmntspgtp apaaeetmtt spgtpapaae etmttspgtp aiegrmdpks cdkthtcppc papellggps vflfppkpkd tlmisrtpev tcvvvdvshe dpevkfnwyv dgvevhnakt kpreeqynst yrvvsvltvl hqdwlngkey kckvsnkalp apiektiska kgqprepqvy tlppsrdelt knqvsltclv kgfypsdiav ewesngqpen nykttppvld sdgsfflysk ltvdksrwqq gnvfscsvmh ealhnhytqk slslspgkhh hhhh
N-terminal Sequence Analysis Ala26 State of Matter Lyophilized Predicted Molecular Mass The predicted molecular weight of Recombinant Human TRAIL R3 is Mr 48 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 75-90 kDa. Predicted Molecular Mass 48 Formulation This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives. Storage and Stability This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. Country of Origin USA Shipping Next Day Ambient NCBI Gene Bank References & Citations1. Fornace Jr., AJ. et al. (1999) Oncogene 18: 4153 2. Büchler, MW. et al. (2001) Anticancer Res. 21: 3153 3. Smith, CA. et al. (1997) J Exp Med. 186: 1165 Technical ProtocolsCertificate of AnalysisIMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein. |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.