Anti-Human TRAIL R3 (Extracellular Domain-1)

Anti-Human TRAIL R3 (Extracellular Domain-1)

Product No.: D246

[product_table name="All Top" skus="D246"]

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Target
TRAIL R3
Product Type
Polyclonal Antibody
Alternate Names
TNF-Related Apoptosis-Inducing Ligand Receptor 3, TRID, TNFRSF10C, CD263, DCR1, LIT, MGC149501, MGC149502
Applications
IHC FFPE
,
WB

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Data

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Rabbit
Immunogen
PN:D263
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human TNF-Related Apoptosis-Inducing Ligand Receptor 3 (TRAIL R3) recognizes Human TRAIL R3. This polyclonal antibody was purified using affinity chromatography.
Background
TNF-related apoptosis-inducing ligand receptor 3 (TRAIL R3) is an antagonist decoy receptor1 that can inhibit TRAIL-induced apoptosis.2 TRAIL R3 is a plasma membrane-bound protein capable of high affinity interaction with the TRAIL ligand.3

Antigen Details

PubMed

References & Citations

1. Fornace Jr., AJ. et al. (1999) Oncogene 18: 4153
2. Büchler, MW. et al. (2001) Anticancer Res. 21: 3153
3. Smith, CA. et al. (1997) J Exp Med. 186: 1165
IHC FFPE
General Western Blot Protocol
Products are for research use only. Not for use in diagnostic or therapeutic procedures.