Recombinant Mouse M-CSF

Home/Recombinant Proteins/Recombinant Mouse M-CSF

Pricing & Details

Product. No.M1098
Alternate Names
CSF-1, MGI-IM, MGC31930, Csfm, C87615
Expression Host
E. coli
Prod No.
Add to cart
M1098-10 µg
10 µg
In stock
Min: 1
Step: 1
M1098-50 µg
50 µg
In stock
Min: 1
Step: 1
M1098-500 µg
500 µg
In stock
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.


Macrophage colony-stimulating factor, or M-CSF, is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. M-CSF is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. It enhances cytotoxicity, superoxide production, phagocytosis, chemotaxis, and secondary cytokine production in monocytes and macrophages.1 It binds to the Colony stimulating factor 1 receptor. M-CSF is known as one of the factors essential for osteoclast development.2

Protein Details

>97% by SDS-PAGE and analyzed by silver stain.
Endotoxin Level
<1.0 EU/µg as determined by the LAL method
Biological Activity
The biological activity of Mouse M-CSF was determined by a cell proliferation assay using an M-CSF-dependent murine monocytic cell line, M-NFS-60 (Halenbeck, R. et al., 1989, Biotechnology 7:710 - 715). The expected ED50 for this effect is typically 0.5 - 1.5 ng/ml.
Expression Host
E. coli
Protein Accession No.
Amino Acid Sequence
mkevsehcs hmignghlkv lqqlidsqme tscqiafefv dqeqlddpvc ylkkafflvq diidetmrfk dntpnanate rlqelsnnln scftkdyeeq nkacvrtfhe tplqllekik nffnetknll ekdwniftkn cnnsfakcss rdvvtkpdcn clypkatpss dpasasphqp papsmaplag lawddsqrte gssllpselp lriedpgsak qrpprstcqt le
N-terminal Sequence Analysis
State of Matter
Predicted Molecular Mass
The predicted molecular weight of Recombinant Mouse M-CSF is Mr 26 kDa. However, the actual molecular weight of the biologically active disulfide-linked homodimeric protein as observed by migration on SDS-PAGE is Mr 29 kDa.
This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
Storage and Stability
This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Country of Origin
Next Day Ambient

References & Citations

1. Nemunaitis, J. et al. (1998) Clin. Infect. Dis. 26: 1279
2. Ko, JS. et al. (2002) Exp Mol Med 34: 340
IMPORTANT Use lot specific datasheet for all technical information pertaining to this recombinant protein.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Leinco Technologies uses cookies to improve your experience and our website service. By continuing to browse our website, you accept our cookie policy. Ok