Anti-Hsp47 Antibody (11141)

Anti-Hsp47 Antibody (11141)

Product No.: 11141

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Clone
1C4-1A6
Target
Hsp47
Formats AvailableView All
Product Type
Monoclonal
Isotype
Mouse IgG1
Applications
WB,ELISA

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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Immunogen
Full-length human Hsp47 (accession no.NP_001193943).
Product Concentration
1.0 mg/ml
Formulation
PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.Purified by Protein G affinity chromatography.
State of Matter
Liquid
Product Preparation
Purified by Protein G affinity chromatography
Storage and Handling
This antibody is stable for at least one (1) year at -20°C. Avoid repeated freeze-thaw cycles.
Regulatory Status
Research Use Only
Country of Origin
USA
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco
Immunoblotting: use at 1ug/ml. A band of ~47kDa is detected

ELISA: use at 1-10ug/ml with Hsp47 on the solid phase.

Positive control: heat-shocked HeLa cell lysate.

These are recommended concentrations.

End users should determine optimal concentrations for their applications.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Description

Specificity
This antibody recognizes human Hsp47.
Background
Hsp47 is a chaperone protein and member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, it is a stress protein localized in the endoplasmic reticulum and plays an active role in intracellular folding, assembly, and secretion of pro- collagens. Expression of Hsp47 is increased at sites of fibrotic lesions.
NCBI Gene Bank ID
UniProt.org
Research Area
Heat Shock & Stress Proteins

References & Citations

Formats Available

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Prod No.
Description
11141
Disclaimer AlertProducts are for research use only. Not for use in diagnostic or therapeutic procedures.