Antibody DetailsProduct DetailsReactivity Species Human Host Species Mouse Product Concentration 0.5 mg/ml Formulation This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This purified antibody is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day Ambient RRIDAB_2828600 Applications and Recommended Usage? Quality Tested by Leinco FC The suggested concentration for this UCHM-1 antibody for staining cells in flow cytometry is ≤ 1.0 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. Other Applications Reported In Literature ? IHC (Frozen) Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Clone UCHM-1 recognizes an epitope on human CD14. Antigen Distribution CD14 is expressed on monocytes, macrophages, dendritic cells, and granulocytes. Background Cluster of differentiation 14 also known as CD14 is a cell surface glycoprotein1 expressed in monocytes, macrophages, polymorphonuclear neutrophils, chondrocytes2, B-cells3, dendritic cells.4 CD14 functions to enhance activation of cells by lipopolysaccharide (LPS).5 Antigen DetailsProtein Ligand/Receptor LPS PubMed NCBI Gene Bank ID UniProt.org Research Area Cell Biology . Immunology . Neuroinflammation . Neuroscience References & Citations1. Ulrich Costabel et al. (1995) CHEST 108: 1614
2. Ulevitch RJ et al. (1993) Immunobiology 187: 227
3. Schumann RR et al. (1994) Medical Microbiol Immunol. 183: 279
4. Verhasselt V et al. (1997) J Immunol. 158: 2919
5. Kirkland TN et al. (2000) J Biol Chem. 275: 3144 Technical Protocols  |
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