Anti-Human CD14 – DyLight® 755

Pricing & Details

Product No.C1865
Clone
UCHM-1
Protein
CD14
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
P35, LPS Receptor
Isotype
Mouse
IgG2a
Applications
FC
Prod No.
Size
Price
Avail.
Qty
Add to cart
C1865-50 µg
50 µg
$85.00
In stock
Max:
Min: 1
Step: 1
C1865-100 µg
100 µg
$150.00
In stock
Max:
Min: 1
Step: 1
C1865-200 µg
200 µg
$250.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Mouse
Product Concentration
0.1 mg/ml
Formulation
This DyLight® 755 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This DyLight® 755 conjugate is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day 2-8°C
Applications and Recommended Usage?
Quality Tested by Leinco
FC The suggested concentration for this UCHM-1 antibody for staining cells in flow cytometry is ≤ 1.0 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Clone UCHM-1 recognizes an epitope on human CD14.
Antigen Distribution
CD14 is expressed on monocytes, macrophages, dendritic cells, and granulocytes.
Background
CD14 is a 53-55 kD GPI-anchored single chain glycoprotein that plays a role in the clearance of gram-negative pathogens by interacting with other proteins, including TLR-4 and MD-2, to mediate the innate immune response to bacterial lipopolysaccharide (LPS). As a high-affinity receptor for LPS, it is involved in the upregulation of adhesion molecules and cytokine expression in monocytes and neutrophils.

Antigen Details

Protein
Ligand/Receptor
LPS.
PubMed
NCBI Gene Bank ID
Research Area
Cell Biology
.
Immunology
.
Neuroinflammation
.
Neuroscience

References & Citations

1. Ulrich Costabel et al. (1995) CHEST 108: 1614 2. Ulevitch RJ et al. (1993) Immunobiology 187: 227 3. Schumann RR et al. (1994) Medical Microbiol Immunol. 183: 279 4. Verhasselt V et al. (1997) J Immunol. 158: 2919 5. Kirkland TN et al. (2000) J Biol Chem. 275: 3144
Flow Cytometry

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.