Anti-Human CD119 (IFNγ Rα Chain) DyLight® 755

Anti-Human CD119 (IFN-γ Rα Chain) – DyLight® 755

Product No.: I-975


Clone GIR-208 Target IFNγ Rα Formats AvailableView All Product Type Monoclonal Antibody Alternate Names Interferon Gamma R Alpha Chain, CD119 Isotype IgG1 Applications FC


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Antibody Details Product Details Reactive Species Human Host Species Mouse Immunogen Purified Recombinant Human IFNGR1 (>98%) Product Concentration 0.1 mg/ml Formulation This DyLight^® 755 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This DyLight^® 755 conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day 2-8°C RRIDAB_2831051 Applications and Recommended Usage? Quality Tested by Leinco FC The suggested concentration for clone GIR-208 conjugated antibody for staining cells in flow cytometry is ≤ .25 μg per 10⁶ cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. Description Description Specificity Clone GIR-208 recognizes an epitope on human IFNγ Rα. Background IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription. Antigen Distribution The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes. NCBI Gene Bank ID 3459 UniProt.org Information on Uniprot.org Research Area Immunology References & Citations View product citations for antibody I-975 on CiteAb Technical Protocols Certificate of Analysis Request COA

Antibody Details

Product Details

Reactive Species

Human

Host Species

Mouse

Immunogen

Purified Recombinant Human IFNGR1 (>98%)

Product Concentration

0.1 mg/ml

Formulation

This DyLight^® 755 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.

Storage and Handling

This DyLight^® 755 conjugate is stable when stored at 2-8°C. Do not freeze.

Country of Origin

USA

Shipping

Next Day 2-8°C

RRIDAB_2831051

Applications and Recommended Usage?
Quality Tested by Leinco

FC The suggested concentration for clone GIR-208 conjugated antibody for staining cells in flow cytometry is ≤ .25 μg per 10⁶ cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.

Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity

Clone GIR-208 recognizes an epitope on human IFNγ Rα.

Background

IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.

Antigen Distribution

The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.

NCBI Gene Bank ID

3459

UniProt.org

Information on Uniprot.org

Research Area

Immunology

References & Citations

View product citations for antibody I-975 on CiteAb

Certificate of Analysis

Request COA

Formats Available

Prod No.	Description
I-977	Anti-Human CD119 (IFN-γ Rα Chain) – PerCP
I-442	Anti-Human CD119 (IFN-γ Rα Chain) – Purified
I-969	Anti-Human CD119 (IFN-γ Rα Chain) – DyLight® 488
I-970	Anti-Human CD119 (IFN-γ Rα Chain) – DyLight® 550
I-971	Anti-Human CD119 (IFN-γ Rα Chain) – DyLight® 594
I-973	Anti-Human CD119 (IFN-γ Rα Chain) – DyLight® 650
I-975	Anti-Human CD119 (IFN-γ Rα Chain) – DyLight® 755
I-441	Anti-Human CD119 (IFN-γ Rα Chain)-PE
I-443	Anti-Human CD119 (IFN-γ Rα Chain) – Purified in vivo GOLD™ Functional Grade
G737	Anti-Human CD119 (IFN-γ Rα Chain) – Purified in vivo PLATINUM™ Functional Grade

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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Anti-Human CD119 (IFN-γ Rα Chain) – DyLight® 755