Antibody DetailsProduct DetailsReactivity Species Human Host Species Mouse Immunogen Purified Recombinant Human IFNGR1 (>98%) Product Concentration 0.1 mg/ml Formulation This DyLight® 755 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This DyLight® 755 conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day 2-8°C RRIDAB_2831051 Applications and Recommended Usage? Quality Tested by Leinco FC The suggested concentration for clone GIR-208 conjugated antibody for staining cells in flow cytometry is ≤ .25 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Clone GIR-208 recognizes an epitope on human IFNγ Rα. Antigen Distribution The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes. Background IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription. Antigen DetailsProtein PubMed NCBI Gene Bank ID UniProt.org Research Area Immunology Technical Protocols |
Formats Available
Prod No. | Description |
|---|---|
I-977 |
|
I-442 |
|
I-969 |
|
I-970 |
|
I-971 |
|
I-973 |
|
I-975 |
|
I-441 |
|
I-443 |
|
G737 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.