Anti-Human IL-17 (Clone 41809)

Pricing & Details

Product No.I-655
Clone
41809
Protein
IL-17
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
Interleukin-17, CTLA8, IL17A
Isotype
Mouse
IgG2b
Applications
ELISA Cap
,
IHC
,
IP
,
N
Prod No.
Size
Price
Avail.
Qty
Add to cart
I-655-25 µg
25 µg
$210.00
In stock
Max:
Min: 1
Step: 1
I-655-100 µg
100 µg
$424.00
In stock
Max:
Min: 1
Step: 1
I-655-500 µg
500 µg
$920.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Mouse
Immunogen
Purified Recombinant Human IL-17 (Accession # Q16552)
Formulation
This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Storage and Handling
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Country of Origin
USA
Shipping
Next Day Ambient
Applications and Recommended Usage?
Quality Tested by Leinco
ELISA Sandwich: This antibody is useful as the capture antibody in a sandwich ELISA. The suggested coating concentration is 2-8 µg/ml. A suitable detection antibody is PN:I-770 at a concentration of approximately 0.1-0.4 µg/ml. A suggested standard for this assay is PN:I-198.
Other Applications Reported In Literature ?
Neutralization: This antibody is useful for neutralization of Human IL-17 bioactivity. The antibody dose required to neutralize 50% (ND50) of the biological activity of Human IL-17 (at 25 ng/ml) is 1-3 µg/ml.
Immunohistochemistry: Suitable for use at concentration of 5-25 µg/mL.
Immunoprecipitation: Suitable for use at concentration of 3 µg/100 µg cell lysate.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Anti-Human Interleukin 17 (IL-17) (Clone 41809) recognizes an epitope on Human IL-17. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background
Interleukin 17 (IL-17) is a T cell cytokine that induces monocyte migration and inflammation.1 IL-17-producing cell could serve as a potential prognostic marker and a novel therapeutic target for hepatocellular carcinoma (HCC).2 IL-17 may be important in recruiting monocytes into the joints of patients with RA, supporting IL-17 as a therapeutic target in RA.1

Antigen Details

Protein
PubMed

References & Citations

1. Pope, RM. et al. (2009) J Immunol. 182: 3884
2. Zheng, L. et al. (2009) J Hepatol. 50(5):980-989.
Elisa Sandwich Protocol
IHC
Immunoprecipitation Protocol

Formats Available

Prod No.
Description
I-655
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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