Anti-Human SMAC (CT)

Pricing & Details

Product No.S483
Protein
SMAC
Formats AvailableView All
Product Type
Polyclonal Antibody
Alternate Names
DIABLO
Applications
IHC FFPE
,
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
S483-20ug
20 µg
$195.00
In stock
Max:
Min: 1
Step: 1
S483-0.1 mg
0.1 mg
$397.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Human
Host Species
Rabbit
Immunogen
PN:S490
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Human Second Mitochondria Derived Activator of Caspase (SMAC) recognizes Human SMAC. This polyclonal antibody was purified using affinity chromatography.
Background
Second Mitochondria Derived Activator of Caspase (SMAC) is a mitochondrial apoptogenic protein that is released to the cytosol in response to diverse apoptotic stimuli, including commonly used chemotherapeutic drugs.1 SMAC promotes cytochrome-c dependent activation by eliminating the inhibition of IAP - a protein that negatively regulates apoptosis or programmed cell death.2

Antigen Details

Protein
PubMed

References & Citations

1. Melendez-Zajgla, J. et al. (2008) J Exp Clin Cancer Res. 26: 27
2. Vucic, D. et al. (2002) J Biol chem. 277: 12275
IHC
General Western Blot Protocol
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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