Anti-Mouse SMAC (CT)
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Rabbit Immunogen PN:S504 Product Concentration 0.5 mg/ml Formulation This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative. Storage and Handling This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. Country of Origin USA Shipping Next Day Ambient RRIDAB_2831754 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Rabbit Anti-Mouse Second Mitochondria Derived Activator of Caspase (SMAC) recognizes Mouse SMAC. This polyclonal antibody was purified using affinity chromatography. Background Second Mitochondria Derived Activator of Caspase (SMAC) is a mitochondrial apoptogenic protein that is released to the cytosol in response to diverse apoptotic stimuli, including commonly used chemotherapeutic drugs.1 SMAC promotes cytochrome-c dependent activation by eliminating the inhibition of IAP - a protein that negatively regulates apoptosis or programmed cell death.2 PubMed References & Citations1. Melendez-Zajgla, J. et al. (2008) J Exp Clin Cancer Res. 26: 27 2. Vucic, D. et al. (2002) J Biol chem. 277: 12275 Technical ProtocolsIHC FFPE  Certificate of Analysis |
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Products are for research use only. Not for use in diagnostic or therapeutic procedures.
