Anti-Mouse Axl

NS0-Derived Recombinant Mouse Axl Extracellular Domain

This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.

The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

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Immunohistochemistry: Suitable for use at concentration of 3-15 µg/mL.

Goat Anti-Mouse Axl recognizes Mouse Axl. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

Axl is a member of receptor tyrosine kinases characterized by an extracellular domains (ECD) resembling cell adhesion molecules and unique sequences in the kinase domain. In addition, Axl is transforming in both fibroblast and hematopoietic cells, and appears to be involved in mesenchymal development.¹ Axl regulates cell migration, phagocytosis and apoptosis.²

1. Liu, ET. et al. (1995) J Mol Biol. 270: 551
2. Berk, BC. et al. (2006) Circ Res. 98: 1446