Anti-Mouse CD19 – PE

Pricing & Details

  
Clone
1D3
Formats AvailableView All
Product Type
Monoclonal Antibody
Isotype
Rat
IgG2a
Applications
FC
Prod No.
Size
Price
Avail.
Qty
Add to cart
C2107-50 µg
50 µg
$55.00
In stock
C2107-100 µg
100 µg
$100.00
In stock
C2107-200 µg
200 µg
$170.00
In stock
  

Antibody Details

Reactivity Species
Mouse
Host Species
Rat
Immunogen
Fusion of NS-1 Myeloma cells with spleen cells
Product Concentration
0.1 mg/ml
Formulation
This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This R-phycoerythrin (R-PE) conjugate is stable when stored at 2-8°C. Do not freeze.
Applications and Recommended Usage ?
(Quality Tested by Leinco)
FC The suggested concentration for this 1D3 antibody for staining cells in flow cytometry is ≤ ≤0.125 μg per 106 cells in a volume of 100 μl. Titration of the reagent is recommended for optimal performance for each application.
Additional Reported Applications For Relevant Conjugates
B
IP
For specific conjugates of this clone, review literature for suggested application details.
Excitation Laser
Blue Laser (488 nm) and/or Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Description

Specificity
Clone 1D3 recognizes an epitope on mouse CD19.
Antigen Distribution
CD19 is expressed in the majority of Pro-B cells to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19.
Background
CD19 is a 95 kD transmembrane glycoprotein and member of the Ig superfamily. The antigen serves as an adaptor protein; drawing cytoplasmic signaling proteins to the membrane. It works via the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. Because of its presence on all B cells, CD19 is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for the immunotherapy of lymphoproliferative disorders. Emerging studies indicate that CD19 plays an active role in fueling the growth of these cancers, most notably by stabilizing the concentrations of the MYC oncoprotein, making CD19 an attractive therapeutic target with respect to its downstream signaling.

Antigen Details

Protein
CD19
Ligand/Receptor
CD21, CD81, Leu-13.
PubMed
CD19+1d3
NCBI Gene Bank ID
Flow Cytometry

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.