Anti-Mouse/Human IL-5 – Biotin
Anti-Mouse/Human IL-5 – Biotin
Product No.: I-1062
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Clone TRFK5 Target IL-5 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names BCDFII,Interleukin-5, IL5, B cell differentiation factor 1, TRF, EDF Isotype IgG2a κ Applications ELISA Det , ELISPOT Det , FC |
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Rat Immunogen Purified Recombinant Mouse IL-5 (>98%) Product Concentration 0.5 mg/ml Formulation This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This biotinylated antibody is stable e.when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day 2-8°C RRIDAB_2830395 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Clone TRFK5 recognizes mouse/human IL-5. Background IL-5 is a 26 kD TH2 cytokine and a homodimeric glycoprotein that is part of the hematopoietic family. IL-5 stimulates B cell growth as well as increases Ig secretion. It is the main factor that promotes the terminal differentiation of eosinophil progenitors and enhances the effector capacity of mature eosinophils. IL-5 is a major regulator of eosinophil accumulation in tissues. In fact, in Hodgkin lymphoma, the characteristically observed eosinophilia is suspected to result from an increased production of IL-5. IL-5 may also be the cause of several allergic diseases including asthma, where it is thought that eosinophils have a significant role in the disease pathology. There are several mAbs currently in use that target IL-5 for the treatment of severe eosinophilic asthma. Antigen DetailsPubMed NCBI Gene Bank ID UniProt.org Research Area Immunology Technical ProtocolsELISA Det ELISPOT Det  |
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I-1038 | |
I-1063 | |
I-1064 | |
I-1062 | |
I-1060 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
