Anti-Mouse SIGIRR (CT)

Pricing & Details

Product No.S556
Protein
SIGIRR
Formats AvailableView All
Product Type
Polyclonal Antibody
Alternate Names
Single Ig IL-1R-Related Molecule, MGC110992, TIR8
Applications
WB
Prod No.
Size
Price
Avail.
Qty
Add to cart
S556-20ug
20 µg
$195.00
In stock
Max:
Min: 1
Step: 1
S556-0.1 mg
0.1 mg
$397.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Mouse
Host Species
Rabbit
Immunogen
PN:S559
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
Shipping
Next Day Ambient
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Rabbit Anti-Mouse Single Immunoglobulin Domain-Containing IL-1 Receptor-Related Protein (SIGIRR) recognizes Mouse SIGIRR. This polyclonal antibody was purified using affinity chromatography.
Background
Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, also known as SIGIRR is a member of the IL-1 receptor family.1 It acts as a negative regulator of interleukin (IL)-1 and lipopolysaccharide (LPS) signaling.2 It also plays a critical role in gut homeostasis, intestinal inflammation, and colitis-associated tumorigenesis by maintaining the microbial tolerance of the colonic epithelium.3

Antigen Details

Protein
PubMed

References & Citations

1. Mantovani, A. et al. (2003) Eur Cytokine Netw. 14: 211
2. Li, X. et al. (2005) J Biol chem. 280: 25233
3. Li, X. et al. (2007) Immunity 26: 461
General Western Blot Protocol
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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