Anti-Human CD57 (Clone VC1.1) – DyLight® 650

Anti-Human CD57 (Clone VC1.1) – DyLight® 650

Product No.: C2073

[product_table name="All Top" skus="C2073"]

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Clone
VC1.1
Target
CD57
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
HNK-1, Natural Killer Cells
Isotype
IgM
Applications
FC

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Product Size
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Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Immunogen
Purified Recombinant Human CD57 (>98%)
Product Concentration
0.2 mg/ml
Formulation
This DyLight® 650 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This DyLight® 650 conjugate is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day 2-8°C
Excitation Laser
Red Laser (652 nm)
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Anti-Human CD57 (Clone VC1.1) recognizes an epitope on Human CD57. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution
The CD57 antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60%) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system.
Background
Anti-CD57 may be used in flow cytometry, Western blotting and immunohistology on formalin fixed paraffin embedded tissue sections. The antibody is useful for enumeration of NK subsets and T-lymphocyte subsets, studies of neural tissue, malignant tissues and AIDS-related complex.

Antigen Details

Ligand/Receptor
Binds to L-selectin and P-selectin in a calcium-dependent manner, also binds to second globular domain of E8 laminin fragment.
PubMed
NCBI Gene Bank ID
Research Area
Costimulatory Molecules
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Immunology

References & Citations

1. Barnstable, C. et al. (1995) Brain Research 559:118 2. Leukocyte Typing V (1995) Oxford University Press: Code No. NK67 3. Arimatsu, Y. et al. (1987) J. Neuroscience 7:1250 4. Abo, T., and Balch, C.M. et al. (1981) J. Immunol. 127:1024
Flow Cytometry

Formats Available

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Products are for research use only. Not for use in diagnostic or therapeutic procedures.