Anti-Human CD57 (Clone VC1.1) – DyLight® 755
Anti-Human CD57 (Clone VC1.1) – DyLight® 755
Product No.: C2075
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Clone VC1.1 Target CD57 Formats AvailableView All Product Type Monoclonal Antibody Alternate Names HNK-1, Natural Killer Cells Isotype IgM Applications FC |
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Antibody DetailsProduct DetailsReactive Species Human Host Species Mouse Immunogen Purified Recombinant Human CD57 (>98%) Product Concentration 0.1 mg/ml Formulation This DyLight<sup>®</sup> 755 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This DyLight® 755 conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day 2-8°C RRIDAB_2829154 Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Mouse Anti-Human CD57 (Clone VC1.1) recognizes an epitope on Human CD57. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Anti-CD57 may be used in flow cytometry, Western blotting and immunohistology on formalin fixed paraffin embedded tissue sections. The antibody is useful for enumeration of NK subsets and T-lymphocyte subsets, studies of neural tissue, malignant tissues and AIDS-related complex. Antigen Distribution The CD57 antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60%) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system. Ligand/Receptor Binds to L-selectin and P-selectin in a calcium-dependent manner, also binds to second globular domain of E8 laminin fragment. PubMed NCBI Gene Bank ID UniProt.org Research Area Costimulatory Molecules . Immunology References & Citations1. Barnstable, C. et al. (1995) Brain Research 559:118
2. Leukocyte Typing V (1995) Oxford University Press: Code No. NK67
3. Arimatsu, Y. et al. (1987) J. Neuroscience 7:1250
4. Abo, T., and Balch, C.M. et al. (1981) J. Immunol. 127:1024 Technical ProtocolsCertificate of Analysis |
Formats Available
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Prod No. | Description |
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C2077 | |
C287 | |
C288 | |
C289 | |
C2069 | |
C2070 | |
C2071 | |
C2073 | |
C2075 | |
C290 | |
C325 |
Products are for research use only. Not for use in diagnostic or therapeutic procedures.