Anti-Human CD57 (Clone VC1.1) – DyLight® 755

Anti-Human CD57 (Clone VC1.1) – DyLight® 755

Product No.: C2075

[product_table name="All Top" skus="C2075"]

- -
- -
Clone
VC1.1
Target
CD57
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
HNK-1, Natural Killer Cells
Isotype
IgM
Applications
FC

- -
- -
Product Size
- -
- -

Antibody Details

Product Details

Reactive Species
Human
Host Species
Mouse
Immunogen
Purified Recombinant Human CD57 (>98%)
Product Concentration
0.1 mg/ml
Formulation
This DyLight<sup>®</sup> 755 conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Handling
This DyLight® 755 conjugate is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day 2-8°C
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
Mouse Anti-Human CD57 (Clone VC1.1) recognizes an epitope on Human CD57. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution
The CD57 antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60%) and on a subset of T-lymphocytes. This carbohydrate is also present on N-CAM in the nervous system.
Background
Anti-CD57 may be used in flow cytometry, Western blotting and immunohistology on formalin fixed paraffin embedded tissue sections. The antibody is useful for enumeration of NK subsets and T-lymphocyte subsets, studies of neural tissue, malignant tissues and AIDS-related complex.

Antigen Details

Ligand/Receptor
Binds to L-selectin and P-selectin in a calcium-dependent manner, also binds to second globular domain of E8 laminin fragment.
PubMed
NCBI Gene Bank ID
Research Area
Costimulatory Molecules
.
Immunology

References & Citations

1. Barnstable, C. et al. (1995) Brain Research 559:118 2. Leukocyte Typing V (1995) Oxford University Press: Code No. NK67 3. Arimatsu, Y. et al. (1987) J. Neuroscience 7:1250 4. Abo, T., and Balch, C.M. et al. (1981) J. Immunol. 127:1024
Flow Cytometry
Products are for research use only. Not for use in diagnostic or therapeutic procedures.