Anti-Mouse IFN-γ (Clone XMG1.2) – APC
Anti-Mouse IFN-γ (Clone XMG1.2) – APC
Product No.: I-1122
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Clone XMG1.2 Target IFN-γ Formats AvailableView All Product Type Monoclonal Antibody Alternate Names Immune Interferon, Type II Interferon, T Cell Interferon, MAF, IFNG, IFG, IFI Isotype IgG1 Applications ICFC |
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Antibody DetailsProduct DetailsReactive Species Mouse Host Species Rat Immunogen Purified Recombinant Mouse IFN-γ (>98%) Product Concentration 0.2 mg/ml Formulation This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This Allophycocyanin (APC) conjugate is stable when stored at 2-8°C. Do not freeze.This APC conjugate is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day 2-8°C Excitation Laser Red Laser (650 nm) RRIDAB_2830458 Additional Applications Reported In Literature ? ICFC The suggested concentration for clone XMG1.2 FITC conjugated antibody for staining cells in Intracellular Immunofluorescent flow cytometry is ≤ 1.0 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionDescriptionSpecificity Rat Anti-Mouse Interferon Gamma (IFN-γ) (Clone XMG1.2) recognizes an epitope on Mouse IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.3 PubMed NCBI Gene Bank ID UniProt.org Research Area Cell Biology . Immunology . Neuroinflammation . Neuroscience References & Citations1. Goeddel DV et al. (1982) Nature 298: 859 2. Wilson CB et al. (2007) Adv. Immunol. 96: 41 3. Hume DA et al. (2004) J Leukoc Biol. 75: 163 4. Teijaro et al. (2020) bioRxiv 22: 24 5. Feldmann et al. (2021) Microorganisms 9(2): 279 |
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Formats Available
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Prod No. | Description |
---|---|
I-1124 | |
I-1123 | |
I-1122 | |
I-1120 | |
I-1104 | |
I-1121 | |
I-1125 | |
I-1126 | |
I-1127 | |
I-1128 | |
I-1119 | |
I-1209 |