Anti-Mouse IFN-γ (Clone XMG1.2) – Biotin
Pricing & Details
Antibody DetailsProduct DetailsReactivity Species Mouse Host Species Rat Immunogen Purified Recombinant Mouse IFN-γ (>98%) Product Concentration 0.5 mg/ml Formulation This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. Storage and Handling This Biotin conjugate is stable when stored at 2-8°C. Do not freeze.This biotinylated antibody is stable when stored at 2-8°C. Do not freeze. Country of Origin USA Shipping Next Day 2-8°C RRIDAB_2830457 Applications and Recommended Usage? Quality Tested by Leinco ELISA Det Other Applications Reported In Literature ? ICFC The suggested concentration for clone XMG1.2 Biotin conjugated antibody for staining cells in Intracellular Immunofluorescent flow cytometry is ≤ 1.0 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application. ELISPOT Det Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change. DescriptionSpecificity Rat Anti-Mouse Interferon Gamma (IFN-γ) (Clone XMG1.2) recognizes an epitope on Mouse IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. Background Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.3 Antigen DetailsProtein PubMed NCBI Gene Bank ID UniProt.org References & Citations1. Goeddel DV et al. (1982) Nature 298: 859 2. Wilson CB et al. (2007) Adv. Immunol. 96: 41 3. Hume DA et al. (2004) J Leukoc Biol. 75: 163 4. Teijaro et al. (2020) bioRxiv 22: 24 5. Feldmann et al. (2021) Microorganisms 9(2): 279 Technical Protocols |
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