Anti-Mouse Vγ2 TCR – FITC

Pricing & Details

Product No.T212
Clone
UC3-10A6
Protein
Vγ 2 T-Cell Receptor
Formats AvailableView All
Product Type
Monoclonal Antibody
Alternate Names
Vγ2 T-cell receptor, T cell receptor gamma 2
Isotype
Armenian Hamster
IgG
Applications
FC
Prod No.
Size
Price
Avail.
Qty
Add to cart
T212-50 µg
50 µg
$104.00
In stock
Max:
Min: 1
Step: 1
T212-500 µg
500 µg
$214.00
In stock
Max:
Min: 1
Step: 1
Bulk quantities available. Contact us for pricing.

Antibody Details

Product Details

Reactivity Species
Mouse
Host Species
Armenian Hamster
Immunogen
G8 mouse T cells
Product Concentration
0.2 mg/ml
Formulation
This Fluorescein (FITC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Product Preparation
The antibody was purified by protein a affinity chromatography, and conjugated with FITC under optimal conditions.
Storage and Handling
This FITC monoclonal antibody conjugate is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Shipping
Next Day Ambient
Excitation Laser
Blue Laser (490 nm)
Applications and Recommended Usage?
Quality Tested by Leinco
Flow Cytometry: This antibody has been quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. Each lot of this antibody is quality control tested.
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity
This antibody reacts with Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes.
Antigen Distribution
Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of γδ TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung.
Background
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.

Antigen Details

Function
Might play a role in a previously unrecognized form of immunological surveillance for stress-induced self-antigens.
Research Area
Adaptive Immunity
.
Immunology

References & Citations

Hedrick, S. M. et al. (1990) Nature. 343:714
Flow Cytometry

Formats Available

Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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